1,519
14
Essay, 2 pages (300 words)

Blood coagulation

Advertising We'll write a high-quality original custom paper on Blood coagulation just for you with a 15% discount for the 1st order Use a Discount Use a Discount

Coagulation of the blood is a process that prevents excess loss of blood from the body. The coagulation process occurs as a result of two steps: The first, Primary Homeostasis, is characterized by activation of the platelets for the formation of a plug at the punctured site. On being punctured, the von Willebrand Factor (vWF) of the body tissues become exposed resulting into the gathering of the collagen and other coagulating factors. The circulating platelets then adhere to the collagen; subsequently, a series of reactions producing other materials that cause more adhesion of collagen and platelets ensue.

More materials are then released by the bound platelets boosting their clumping thus helping the plug formation (Bose, 2011) Another step, Secondary Homeostasis, is characterized by a cascade of reactions that help in the formation of fibrin. This process is achieved by either the Intrinsic Pathway or the Extrinsic Pathway. Both this processes are necessary for producing prothrombin activator that furthers the coagulation process with the latter being more rapid. Moreover, the two steps above converge into a common pathway that aims to form thrombin. Plasma proteins fibrinogen and prothrombin are produced in the liver in an inactive form.

The prothrombin factor is instrumental in converting them into their active forms. First, it converts prothrombin to thrombin which in turn converts fibrinogen into fibrin strands. The fibrin strands creates a mesh that offers a structural support for the platelet plug made at the punctured site thus ending the coagulation process (Bose, 2011). At times, blood coagulation may occur uncontrollably due to some disorders. These results into a condition called thrombosis. This situation can be remedied by the introduction of anti-coagulants like Antithrombin III which inhibits thrombin formation by binding to prothrombin, factor 9 and 10 thus inactivating them.

Heparin is another anticoagulant that enhances the functioning of Antithrombin III by binding to it to cause an allosteric change thus developing a higher affinity for thrombin (King, 2012).

Thanks for Voting!
Blood coagulation. Page 1
Blood coagulation. Page 2
Blood coagulation. Page 3

The paper "Blood coagulation" was written by a real student and voluntarily submitted to this database. You can use this work as a sample in order to gain inspiration or start the research for your own writing. You aren't allowed to use any part of this example without properly citing it first.

If you are the author of this paper and don't want it to be used on EduPony, contact us for its removal.

Ask for Removal

Cite this Essay

References

EduPony. (2022) 'Blood coagulation'. 25 January.

Reference

EduPony. (2022, January 25). Blood coagulation. Retrieved from https://edupony.com/blood-coagulation/

References

EduPony. 2022. "Blood coagulation." January 25, 2022. https://edupony.com/blood-coagulation/.

1. EduPony. "Blood coagulation." January 25, 2022. https://edupony.com/blood-coagulation/.


Bibliography


EduPony. "Blood coagulation." January 25, 2022. https://edupony.com/blood-coagulation/.

Work Cited

"Blood coagulation." EduPony, 25 Jan. 2022, edupony.com/blood-coagulation/.

Contact EduPony

If you have any suggestions on how to improve Blood coagulation, please do not hesitate to contact us. We want to know more: [email protected]